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Recommended Products for You
High Potency Optimized Folate
L-Methylfolate
8500 mcg DFE, 30 vegetarian tablets Item # 01913
Heart & brain health, homocysteine support, strong dose
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High Potency Optimized Folate
L-Methylfolate
8500 mcg DFE, 30 vegetarian tablets Item # 01913
Heart & brain health, homocysteine support, strong dose
Save 11%
First shipment within 1 business day with FREE standard shipping.
Frequently Bought Together
- This Item: High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets
- Vitamin B12 Methylcobalamin, 5 mg, 60 vegetarian lozenges
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What is High Potency Optimized Folate?
Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with both cardiovascular and cognitive health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Our formula provides 5-MTHF, so you don’t have to.
The 5-MTHF folate in High Potency Optimized Folate is an ultra-bioavailable form of the B-vitamin commonly called folic acid.
High Potency Optimized Folate Benefits
- Super high-potency dose of bioavailable 5-MTHF folate
- Supports both cardiovascular & cognitive health
- Helps maintain already-healthy homocysteine levels
- 5-MTHF folate overcomes the enzyme inefficiency roadblock
For the Greatest Health Benefits
Folic acid is a common B-vitamin supplement. Once ingested, your body is supposed to convert folic acid into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that’s necessary to do this. So we formulated High Potency Optimized Folate with 8500 mcg of 5-MTHF, saving your body the trouble.
Life Extension - Why Do We Do It?
The Best Supplements Science Can Offer
When putting something in your body, you should be confident that you’re getting the nutritional benefits your body deserves. We've been delivering the highest-quality products—backed by science and formulated with the finest ingredients—for over 40 years.
What Matters to You, Matters to Us
We're committed to empowering you to live a healthier life. Whether it’s finding sustainable partners for our ingredients or funding the latest anti-aging research, we're all about your health & wellness.
Highly Recommended
98% of our customers recommend us to family and friends. We're very proud of that because our loved ones matter to us—and we're willing to bet you feel the same way.
Product Transparency
40 years of research dedicated to bringing you premium, scientifically-validated formulations.
Folic acid is the most common form of folate supplements. Once ingested, your body is supposed to convert folic acid, a synthetic version of folate, into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that's necessary to convert folic acid to 5-MTHF.1-3 A more useful approach is to take 5-MTHF directly.4-6
MoreThese products are not intended to diagnose, treat, cure, or prevent any disease.
°DFE (dietary folate equivalents) Non-GMO |
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Consult your healthcare provider if you are at risk of vitamin B12 deficiency, as high-dose folate may mask signs. |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Actual Size
- Circulation. 2015;132(1):e6-e9.
- European Journal of Medical Genetics. 2015;58(1):1-10.
- Arteriosclerosis, Thrombosis, and Vascular Biology. 1997;17(6):1157-1162.
- The Journal of Nutrition. 2018;148(6):885-890.
- The Journal of Alternative and Complementary Medicine. 2019;25(2):169-180.
- The FASEB Journal. 2017;31(1_supplement):lb399-lb399.
- The American Journal of Clinical Nutrition. 2006;84(1):156-161.
- The American Journal of Clinical Nutrition. 2005;82(3):627-635.
- Dementia and Geriatric Cognitive Disorders. 2001;12(5):309-313.
Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer
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